History, challenges and perspectives of cell microencapsulation.

نویسندگان

  • Gorka Orive
  • Rose Maria Hernández
  • Alicia Rodríguez Gascón
  • Riccardo Calafiore
  • Thomas Ming Swi Chang
  • Paul de Vos
  • Gonzalo Hortelano
  • David Hunkeler
  • Igor Lacík
  • José Luis Pedraz
چکیده

Cell microencapsulation continues to hold significant promise for biotechnology and medicine. The controlled, and continuous, delivery of therapeutic products to the host by immunoisolated cells is a potentially cost-effective method to treat a wide range of diseases. Although there are several issues that need to be addressed, including capsule manufacture, properties and performance, in the past few years, a stepwise analysis on the essential obstacles and limitations has brought the whole technology closer to a realistic proposal for clinical application. This paper summarizes the current situation in the cell encapsulation field and discusses the main events that have occurred along the way.

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عنوان ژورنال:
  • Trends in biotechnology

دوره 22 2  شماره 

صفحات  -

تاریخ انتشار 2004